Erika JENSEN-JAROLIM, MD

jensen2Head of Comparative Medicine, Messerli Research Institute & Institute of Pathophysiology and Allergy Research, Center of Pathophysiology, Infectiology and Immunology
Professor for Comparative Medicine of Medical University Vienna & University of Veterinary Medicine

Education:
MD: University Vienna, Austria
Postdoctoral Training: University Hospital Copenhagen, and Institute of Immunology, University of Bern, Switzerland

Research Interests:
• Interspecies differences in allergy and oncology
• Vaccines & formulations, antibody engineering in allergy, oncology

Biography:
Erika Jensen-Jarolim holds the professorship for Comparative Medicine, a double appointment between the Medical and Veterinary Universities Vienna since August 1st, 2011, at the interdisciplinary Messerli Research Institute. Before she served during 5 years as head of the IPA - Dept. of Pathophysiology and Allergy Research of the Medical University Vienna. She holds an MD, is specialized in pathophysiology and immunology and is member of the senate of the Medical University Vienna, and was member of the university council of the Universiy of Veterinary Medicine Vienna between 2008 and 2011. Her research is dedicated to the evaluation of pathophysiological mechanisms to improve diagnosis and therapy in the allergy, oncology and allergooncology fields. Major highlights were mimotope vaccines and mechanisms of food allergy, as well as more recently, comparative research in terms of the One health principle.

Proposed PhD research projects:
1) Understanding different sensitization patterns to HDM allergens in humans and canines    
2) Investigating the interplay of IgG4 antibodies with macrophages in immune tolerance in humans and canines

Selected publications:

  1. Singer, J., Weichselbaumer, M., Stockner, T., Mechtcheriakova, D., Sobanov, Y., Bajna, E., Wrba, F., Horvat, R., Thalhammer, J.G., Willmann, M., and Jensen-Jarolim, E. (2012). Comparative oncology: ErbB-1 and ErbB-2 homologues in canine cancer are susceptible to cetuximab and trastuzumab targeting. Molecular immunology 50, 200-209. PMID: 22424313
  2. Riemer, A.B., Untersmayr, E., Knittelfelder, R., Duschl, A., Pehamberger, H., Zielinski, C.C., Scheiner, O., and Jensen-Jarolim, E. (2007). Active induction of tumor-specific IgE antibodies by oral mimotope vaccination. Cancer research 67, 3406-3411. PMID: 17409451
  3. Untersmayr, E., Bakos, N., Scholl, I., Kundi, M., Roth-Walter, F., Szalai, K., Riemer, A.B., Ankersmit, H.J., Scheiner, O., Boltz-Nitulescu, G., and Jensen-Jarolim, E. (2005a). Anti-ulcer drugs promote IgE formation toward dietary antigens in adult patients. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 19, 656-658. PMID: 17227952
  4. Roth-Walter, F., Scholl, I., Untersmayr, E., Fuchs, R., Boltz-Nitulescu, G., Weissenbock, A., Scheiner, O., Gabor, F., and Jensen-Jarolim, E. (2004). M cell targeting with Aleuria aurantia lectin as a novel approach for oral allergen immunotherapy. The Journal of allergy and clinical immunology 114, 1362-1368. PMID: 15577836
  5. Ganglberger, E., Grunberger, K., Sponer, B., Radauer, C., Breiteneder, H., Boltz-Nitulescu, G., Scheiner, O., and Jensen-Jarolim, E. (2000a). Allergen mimotopes for 3-dimensional epitope search and induction of antibodies inhibiting human IgE. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 14, 2177-2184. PMID: 11053238

Other Publications extlink