Barbara BOHLE, PhD
Director, Department of Pathophysiology and Allergy Research,
Professor of Cellular Allergology, Medical University of Vienna, Vienna, Austria
Education:
BS: University of Agricultural Sciences, Vienna, Austria
PhD: Department of Pathophysiology
Postdoctoral Training: Department of Pathophysiology and Allergy Research, Medical University of Vienna
Research Interests:
• Role of T cells in allergic disorders
• Development of novel treatment strategies for allergy
Biography
Barbara Bohle is Professor of Cellular Allergology and head of the Department of Pathophysiology and Allergy Research at the Medical University of Vienna in Austria. She also runs the Christian Doppler Laboratory for Immunomodulation. Barbara Bohle obtained her Ph.D. degree in biotechnology from the University of Agricultural Sciences in Vienna in 2000. In 2002 she obtained the venia docendi in immunology and since then she is the head of the team “Allergy Research” at the Department of Pathophysiology and Allergy Research. Prof. Bohle is the author of a number of publications on allergy and immunology with an emphasis on the role of T cells in the initiation, maintenance and cure of allergic disorders. Her work has contributed to a better understanding of the role of T cells in allergic disorders and to the development of novel treatment strategies for allergy. Prof. Bohle serves on the board of the Austrian Society of Allergology and Immunology as well as on the scientific advisory board of the Paul Ehrlich Institute in Langen, Germany. She is one Editor-in-Chief of the international journal “International Archives of Allergy and Immunology”.
Proposed PhD research projects:
1) Allergen-specific antibody responses to SLIT with rBet v 1 and rMal d 1
2) Allergen-specific T cell responses to SLIT with rBet v 1 and rMal d 1
Selected publications:
- Geroldinger-Simic, M., Kinaciyan, T., Nagl, B., Baumgartner-Durchschlag, U., Huber, H., Ebner, C., Lidholm, J., Bartel, D., Vieths, S., Jahn-Schmid, B., and Bohle, B. 2013. Oral exposure to Mal d 1 affects the immune response in patients with birch pollen allergy. J Allergy Clin Immunol. 131: 94-102. PMID: 22921871
- Kitzmuller, C., Nagl, B., Deifl, S., Walterskirchen, C., Jahn-Schmid, B., Zlabinger, G.J., and Bohle, B. 2012. Human blood basophils do not act as antigen-presenting cells for the major birch pollen allergen Bet v 1. Allergy. 67: 593-600. PMID: 22188598
- Schulten, V., Nagl, B., Scala, E., Bernardi, M.L., Mari, A., Ciardiello, M.A., Lauer, I., Scheurer, S., Briza, P., Jurets, A., Ferreira, F., Jahn-Schmid, B., Fischer, G.F., and Bohle, B. 2011. Pru p 3, the nonspecific lipid transfer protein from peach, dominates the immune response to its homolog in hazelnut. Allergy. 66: 1005-1013. PMID: 21352239
- Geroldinger-Simic, M., Zelniker, T., Aberer, W., Ebner, C., Egger, C., Greiderer, A., Prem, N., Lidholm, J., Ballmer-Weber, B.K., Vieths, S., and Bohle, B. 2011. Birch pollen-related food allergy: clinical aspects and the role of allergen-specific IgE and IgG4 antibodies. J Allergy Clin Immunol. 127: 616-622 e611. PMID: 21251701
- Schulten, V., Radakovics, A., Hartz, C., Mari, A., Vazquez-Cortes, S., Fernandez-Rivas, M., Lauer, I., Jahn-Schmid, B., Eiwegger, T., Scheurer, S., and Bohle, B. 2009. Characterization of the allergic T-cell response to Pru p 3, the nonspecific lipid transfer protein in peach. J Allergy Clin Immunol. 124: 100-107. PMID: 19356790
